Evaluation of Long-Term Immunogenicity in Subjects Boosted With a TBE Vaccine for Adults

Novartis179 enrolled

Overview

The purpose of this study it is to evalutate the persistence of antibodies after a booster immunisation with a TBE vaccine for adults

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

179

Conditions

Encephalitis, Tick-Borne

Interventions

Tick-Borne Encephalitis vaccineBIOLOGICAL

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy volunteers of both sexes aged \>18 who participated in another study on TBE vaccination Exclusion Criteria: * Subjects with any condition, in the opinion of the Investigator, might interfere with the evaluation of the study objectives.

Locations (1)

Unnamed facility

Regensburg, Germany

Outcomes

Primary Outcomes

Long-term antibody kinetics as measured both by ELISA and neutralisation test (NT) five years after first booster immunization.

Secondary Outcomes

Booster response in a subset of subjects as measured by NT, ELISA and cellular immunity on Days 3, 5, 7 and 21 after 2nd booster immunization.

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.