Allergy Towards Grass and Bronchial Inflammation - Related to Immunotherapy and Exhaled Nitrogen Oxide

Bispebjerg Hospital40 enrolled

Overview

The purpose of this study is to evaluate the immunomodulatory effect of treatment of allergic rhinitis symptoms with specific immunotherapy by measurement of pulmonary inflammatory markers, and among others, exhaled nitric oxide.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Asthma, Bronchial Allergic Rhinitis Hypersensitivity, Immediate

Interventions

Specific immunotherapyBIOLOGICAL

Eligibility

Sex: ALLMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18-45 years old * Skin prick test or RAS test and physical examination conclude that the patient will have a beneficial effect from specific immunotherapy Exclusion Criteria: * Other diseases except atopic disease * Pregnancy

Locations (1)

Bispebjerg Hospital

Copenhagen, Denmark

RECRUITING

Outcomes

Primary Outcomes

Skin prick test

Spirometry

Methacholine provocation of the pulmonary system

Exhaled nitric oxide

Immunoglobulin E (IgE) status

Sputum examination

Condensation of exhaled air

Secondary Outcomes

Questionnaire

Central Contacts

Thomas B Knudsen, Medical student

CONTACT

+45 61 70 96 99 thomas@uknet.dk

Vibeke Backer, M.D., M.D.Sci

CONTACT

+45 35 31 30 69 backer@dadlnet.dk

Data from ClinicalTrials.gov

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