Quetiapine Fumarate Bipolar Maintenance Monotherapy

Inclusion Criteria: * Signed informed consent * 18 years or older * A diagnosis of Bipolar I Disorder * Have a current manic, depressed or mixed episode * Have had a manic, depressed or mixed episode during the last 26 weeks that was treated with quetiapine * Female patients of childbearing potential must be using a reliable method of contraception Exclusion Criteria: * Pregnancy * Substance or alcohol dependence at enrollment * Unstable thyroid function * Unstable Diabetes * Unstable or inadequately treated medical illness e.g., angina pectoris and hypertension * Use of an experimental drug within 30 days of enrollment