Echocardiographic Study of the Haemodynamic Effects of Remifentanil With and Without Glycopyrrolate in Healthy Children

University Hospital, Ghent63 enrolled

Overview

Study to investigate the influence of remifentanil and glycopyrrolate on cardiac index and blood pressure in children.To differentiate between contractility and the effect of the circulating volume, some of the subjects will receive additional fluid.This will be evaluated using two transthoracic echocardiac exams within the first 30 min of anesthesia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Urological Surgery

Interventions

Administration of remifentanil and glycopyrrolateDRUG

2 mg, intravenius use

Eligibility

Sex: ALLMin age: 1 YearMax age: 6 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * ASA I and II children * 1-6 years * urological surgery Exclusion Criteria: * Cardiac disease * Diabetes

Locations (1)

University Hospital Ghent

Ghent, Belgium

Outcomes

Primary Outcomes

Cardiac index

Time frame: Twice in 16 minutes.

Blood pressure

Time frame: Twice in 16 minutes.

Data from ClinicalTrials.gov

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