The purpose of this study is to describe the joint symptoms and structural joint changes under anastrozole as adjuvant treatment in postmenopausal women with early breast cancer.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
114
1mg/Day oral
Research Site
Bordeaux, France
Research Site
Caen, France
Research Site
Lyon, France
Research Site
Paris, France
Research Site
Poitiers, France
Number of Participants With New Events of Arthralgia
Time frame: 12 months
Functional Index of Cochin at 12 Months in Patients Under Anastrozole.
Functional index of cochin score (from 0 to 90) : sum up of 18 questions on activities involving hands (each question scored from 0 = yes without difficulties (best) to 5 = impossible (worst)) based on 99 patients due to missing values.
Time frame: 12 months
Serum Collagen Degradation Type I - CTX-I at 12 Months in Patients Under Anastrozole
Results are based on 97 patients due to missing values
Time frame: 12 months
Kellgren and Lawrence Score at 12 Months in Patients Under Anastrozole
X ray evaluation of arthritis in 30 articulations ; each articulation scored from (0 = no arthritis to 4 = severe arthritis) based on 92 patients due to missing values
Time frame: 12 months
Synovial Membrane Thickness at 12 Months in Patients Under Anastrozole
X ray assessment on hands and wrists based on 99 patients due to missing values
Time frame: 12 months
Percentage of Participant With Therapeutic Maintenance Under Anastrozole
Treatment compliance. results based on 109 patients due to missing values
Time frame: 12 months
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