Coronary Artery Revascularization in Diabetes

Inclusion Criteria: Patients with diabetes with severe coronary artery disease General Inclusion Criteria 1. Age at least 18 years old 2. Patients with either Type I or Type II diabetes with a documented HbA1c greater than site ULN (If not on diabetic medication must be confirmed by a blood glucose of \>126 mg/dL fasting, or \>200mg/dL non-fasting); OR on diabetic medication with a documented physician diagnosis of diabetes mellitus. 3. No child bearing potential (if female) 4. Patient competent to provide consent Exclusion Criteria: General Exclusion Criteria 5. Congenital heart disease 6. Coronary bypass surgery within the preceding one year 7. Need for concomitant cardiac surgery 8. AHA Class III decompensated heart failure or AHA Class IV heart failure 9. Undergoing PCI for hemodynamic instability related to acute STEMI 10. History of a hemorrhagic stroke 11. Severe bleeding diathesis 12. History of chronic pancreatitis 13. A severe co-morbid condition that is expected to limit life to less than two years 14. Embolic stroke in the past six months 15. Significant GI bleed within the last one month 16. Lack of adequate surgical conduit 17. Sensitivity to clopidogrel (Plavix) 18. Sensitivity to glycoprotein IIb/IIIa inhibitors 19. Chronic systemic steroid use 20. Participation in another trial with active intervention 21. Patient unable to be adequately followed