Relationship of Genes and Life Events to Blood Pressure

Sunnybrook Health Sciences Centre120 enrolled

Overview

Research suggests that blood pressure is influenced by both genetic and environmental factors. The goal of this study is to find genes that play a role in blood pressure and understand how they interact with life events (such as job stress) to influence blood pressure. We hypothesize that the gene for endothelin-1 is associated with increased blood pressure. Further, we predict that this genetic relationship is moderated by psychosocial stress factors, specifically job strain and marital cohesion.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Hypertension Psychosocial Factors

Interventions

Cheek swab samples for DNAGENETIC

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Previous participation in a study of psychosocial stressors and blood pressure (Double Exposure Study) and agreement to participate in follow-up studies Exclusion Criteria: * Withdrawal of consent

Locations (1)

Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.