The purpose of this study is to investigate the nature of the physiological reasons for the decreases in resting blood pressure that can result from systematic practice of computer-guided breathing exercises or meditative relaxation.
In this randomized clinical trial, persons with moderately elevated blood pressure were trained in either computer-guided breathing exercises or meditative relaxation to breathing. The computer-guided breathing exercise involves listening to tones of ascending and descending pitch to which breathing is entrained to low frequencies over a 15 minute interval. The meditative relaxation involves passive attention to natural breathing for the same duration. Participants will perform these breathing exercises daily at home for four weeks. Before and after the intervention, respiratory, cardiovascular, and urinary endogenous digitalis-like factors will be systematically recorded to determine the extent to which chronic neuroendocrine changes underlie the reductions in blood pressure.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
44
The participant will engage in daily 15 min sessions of meditative relaxation that involves quiet attention to breathing pattern with no attempt to manipulate breathing pattern
The participant will be trained to perform a guided breathing task that involves a chest expansion sensor, battery-powered microcomputer, and earphones
NIA Clinical Research Unit
Baltimore, Maryland, United States
Breathing Rate
Breathing rate was monitored continuously via inductive plethysmography.
Time frame: After 15 minutes of guided breathing or control task
Minute Ventilation
Minute Ventilation was continuously monitored via inductive plethysmography
Time frame: After 15 minutes of guided breathing or control task
End Tidal CO2 (PetCO2)
End tidal CO2 was monitored continuously using a respiratory gas monitor
Time frame: After 15 minutes of guided breathing or control task
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