Efficacy and Safety of Psychopharmacotherapy in Patients With Schizophrenia or Bipolar Disorders

Inclusion Criteria: * Male or female patients, 18-65 years of age. * Patients must have a diagnosis of schizophrenia or bipolar disorder according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). * Patients have not been received antipsychotics or mood stabilizers within the past 4 weeks prior to the study entry. * Each patient must provide written informed consent after full explanation of study protocol, and authorized legal guardian must understand the nature of the study and must also give assent to study participation. Exclusion Criteria: * History of taking antipsychotics or mood stabilizers within past 4 weeks. * History of DSM-IV substance dependence. * Mental retardation (IQ \< 70)or patients who are not able to understand the informed consent. * Definite or suspected organic mental disorders. * Female patients who are not able to maintain contraception during this study * Laboratory abnormalities with clinical significance * History of epilepsy or electroconvulsive therapy within the past 3 months.