Prophylaxis With Caspofungin in High-Risk Liver Transplantation

Inclusion Criteria: * 18 years of age or older * Patient has received an orthotopic liver transplantation * Patient meets criteria, as defined per protocol, for being considered at high risk of developing an invasive fungal infection post-liver transplantation * For women of childbearing potential, patient must have a negative serum or urine pregnancy test Exclusion Criteria: * Any systemic antifungal therapy (other than fluconazole for a maximum of 7 days) within 14 days of the administration of the study drug. * Documented (proven/probable) or suspected (possible) invasive fungal infection at the time of enrollment. * Abnormal laboratory values as defined per protocol. * Allergy, hypersensitivity, or any serious reaction to an echinocandin antifungal. * Patient not expected to survive at least 5 days. * Patient is pregnant or breast feeding.