SLV 308 and Pramipexole for Treatment of Patients With Early Parkinson Disease

Inclusion Criteria: * Diagnosis of idiopathic Parkinson's Disease, Modified Hoehn \& Yahr up to stage III, UPDRS motor score (part III) must have a total of at least 10 at baseline. Exclusion Criteria: * Diagnosis is unclear or a suspicion of other parkinsonian syndromes, * Patients who have undergone surgery for the treatment of PD, * Current presence of dyskinesias, * Motor fluctuations or loss of postural reflexes, * A history of non-response to an adequate course of l-dopa or a dopamine agonist, * Patients for whom previously treatment with dopamine agonists needed to terminate because of induction of psychosis (i.e. hallucinations) and /or sleep attacks.