Opioid Maintenance Medications Comparison Study

Johns Hopkins University220 enrolled

Overview

A 17 week, double-blind, randomized, parallel group, four arm design outpatient study comparing LAAM, buprenorphine and two dose levels of methadone for the treatment of opioid dependence.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

220

Conditions

Opioid Dependence

Interventions

LAAM. buprenorphine and methadoneDRUG

Eligibility

Sex: ALLMin age: 21 YearsMax age: 55 Years

Medical Language ↔ Plain English

Inclusion * age 21 to 55 years * diagnosis of opioid dependence by criteria of the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) * evidence of recent opioid use on toxicologic screening Exclusion * serious medical or psychiatric illness requiring long-term medication * positive pregnancy test

Locations (1)

Behavioral Pharmacology Research Unit; Johns Hopkins Bayview Campus

Baltimore, Maryland, United States

Outcomes

Primary Outcomes

Study retention

Drug use

Secondary Outcomes

Safety

Data from ClinicalTrials.gov

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