Prevention of Radiation Pneumonitis After Three-dimensional Conformal Radiation Therapy (3D-CRT) in Patients With Non-small-cell Lung Cancer

Inclusion Criteria: * Non-metastatic cytologically or histologically proven non-small-cell lung cancer (NSCLC) * Operated NSCLC patients requiring post-surgical irradiation or non-operated NSCLC patients requiring curative irradiation * Conformational thoracic radiotherapy with curative intent * Age \>= 18 * Complete functional respiratory evaluation (FRE) performed less than 2 months before inclusion, demonstrating a maximum expiratory flow-volume/second \> 1 l (in case surgery, the FRE must have been realized in the post-surgery period) * Thoracic CT-scan performed less than 2 months before inclusion for non-operated patient * PET-scan performed less than 2 months before inclusion for non-operated patient * Performance status (PS) ECOG \<= 1 * Possible training on breath holding technique * Female patients of childbearing potential: effective method of contraception necessary * Mandatory affiliation with a social security system * Written, signed, informed consent Exclusion Criteria: * Small-cell lung cancer * Metastatic disease * Infiltrating pulmonary disease * Previous thoracic irradiation * Indication of irradiation with palliative intent * Previous or concurrent primary malignancies at other sites (except basocellular skin cancer or cervical cancer in situ or complete remission for more than 5 years) * Life expectancy \< 6 months * Patient understanding incompatible with the breath-hold technique (patients with major presbycusis are not eligible) * Pregnant or lactating woman * Patient included in another clinical trial * Follow-up difficult * Patient deprived of freedom