To evaluate the efficacy and safety of quetiapine fumarate sustained release (Seroquel SR) in the treatment of Major Depressive Disorder. PLEASE NOTE: Seroquel SR and Seroquel XR refer to the same formulation. The SR designation was changed to XR after consultation with FDA.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
450
To evaluate the efficacy of quetiapine SR compared with placebo in the treatment of patients with major depressive disorder (MDD) as assessed by change from randomisation to week 8 score in the MADRS total score.
If quetiapine SR improves health-related quality of life of patients with MDD, compared to placebo
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Research Site
Edmonton, Alberta, Canada
Research Site
Kelowna, British Columbia, Canada
Research Site
Penticton, British Columbia, Canada
Research Site
Vancouver, British Columbia, Canada
Research Site
St. John's, Newfoundland and Labrador, Canada
Research Site
Halifax, Nova Scotia, Canada
Research Site
Sydney, Nova Scotia, Canada
Research Site
Greater Sudbury, Ontario, Canada
Research Site
Hamilton, Ontario, Canada
Research Site
Oakville, Ontario, Canada
...and 32 more locations