To evaluate the efficacy of quetiapine fumarate sustained release (Seroquel SR™) in combination with an antidepressant versus an antidepressant alone in patients with Major Depressive Disorder. PLEASE NOTE: Seroquel SR and Seroquel XR refer to the same formulation. The SR designation was changed to XR after consultation with FDA.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
494
To evaluate the efficacy of quetiapine fumarate sustained release
(Seroquel SR™) in combination with an antidepressant versus an antidepressant alone in patients with Major Depressive Disorder.
If quetiapine SR in combination with an antidepressant improves health-related quality of life of patients with MDD, compared to an antidepressant alone.
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Research Site
Everton Park, Queensland, Australia
Research Site
Southport, Queensland, Australia
Research Site
Frankston, Victoria, Australia
Research Site
Malvern, Victoria, Australia
Research Site
Prahran, Victoria, Australia
Research Site
Richmond, Victoria, Australia
Research Site
Brisbane, Australia
Research Site
Assebroek, Belgium
Research Site
Brussels, Belgium
Research Site
Ghent, Belgium
...and 62 more locations