The purpose of this study is to investigate the clinical efficacy of 3% (w/w) GW842470X cream applied to involved skin of adult patients with moderate atopic dermatitis using the Eczema Area Severity Index (EASI) assessment of disease severity and to investigate the safety of and tolerability of 3% GW842470X cream on diseased skin of adult patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
190
GSK Investigational Site
Augsburg, Bavaria, Germany
GSK Investigational Site
Mahlow, Brandenburg, Germany
GSK Investigational Site
Hamburg, Free and Hanseatic City of Hamburg, Germany
Clinical efficacy of 3% GW842470X cream applied to involved skin of adult patients with moderate atopic dermatitis using the Eczema Area Severity Index (EASI).
Safety and tolerability of 3% GW842470X cream
Clinical efficacy using SCORing Atopic Dermatitis score & Investigators Global Assessment Scale
Symptoms: pruritus & sleep loss
Characterize systemic exposure to GW842470X following 21 days treatment.
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GSK Investigational Site
Hamburg, Free and Hanseatic City of Hamburg, Germany
GSK Investigational Site
Hamburg, Free and Hanseatic City of Hamburg, Germany
GSK Investigational Site
Duelmen, Lower Saxony, Germany
GSK Investigational Site
Cologne, North Rhine-Westphalia, Germany
GSK Investigational Site
Schenefeld, Schleswig-Holstein, Germany
GSK Investigational Site
Berlin, State of Berlin, Germany
GSK Investigational Site
Berlin, State of Berlin, Germany
...and 3 more locations