Azithromycin Level in Tears and in Conjunctiva in 36 Healthy Volunteers

Inclusion Criteria: * Written informed consent; * Healthy volunteers; * Registered in the national register of healthy volunteers; * Male or female aged from 18 to 45 years old; * Able to understand the study instructions; * Likely to comply with the study schedule and treatment; * Normal subjective ocular symptoms, Schirmer test \> 10 mm in 5 min and corrected visual acuity \>= 6/10 in both eyes Exclusion Criteria: * Ocular trauma, infection or inflammation within the last 3 months; * Blepharitis; * Conjunctival hyperaemia (score \>= 2); * Fluorescein-stained punctuations (score \>= 1b); * Hypersensitivity to one of the products used in the study; * Clinically relevant allergy; * Medical or surgical history incompatible with the study; * Recent acute illness; * Ocular surgery, including LASIK, LASEK and PRK within the last 12 months; * Other ocular lasers or Zithromax® or Azadose® within the last 3 months; * Systemic antibiotics and ocular medications within the last month; * Contact lenses within the last week; * Any medication on Day 0 and during the study (except paracetamol and contraceptives).