Use of Cone Beam Kilovoltage Imaging in Patients Receiving Radiation Therapy for Head and Neck Cancer

Phase 2TerminatedNCT00358007

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University30 enrolled

Overview

To evaluate the use of cone beam computed tomography in treating head and neck to hopefully reduce side effects

The general purpose of this study is to evaluate Kilovoltage (kv) Imaging, specifically the Cone-beam CT (CBCT) scan device, to assess the accuracy of radiation therapy treatment delivery for patients with head and neck neoplasms

Study Type

INTERVENTIONAL

Allocation

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Head and Neck Neoplasms

Interventions

PTV ReductionDEVICE

The margin around the area to be treated with radiation is decreased due the image guidance of the cone beam CT

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * any patient receiving radiation therapy for a head and neck tumor assigned to the new Elekta Synergy Linare Accelerator Exclusion Criteria: * NA

Locations (1)

Thomas Jefferson University

Philadelphia, Pennsylvania, United States

Outcomes

Primary Outcomes

Average Interfraction Shift of Patients Undergoing Radiotherapy

Determine the magnitude of the systematic error of patient positioning as determined by cone beam CT (CBCT) and the desired placement based on the treatment planning CT scan. Every day, prior to radiation treatment, a CBCT will be performed. The CBCT images will be compared to the radiation therapy planning CT image just taken.

Time frame: Daily prior to radiation

Average Residual Error Motion of Patients Undergoing Radiotherapy

To determine the magnitude of random variance (random error) in radiotherapy treatment of head and neck neoplasms

Time frame: Daily after each radiotherapy treatment

Data from ClinicalTrials.gov

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