Blood Collection From Individuals With Lung Disease for Genetic Studies

Weill Medical College of Cornell University3,087 enrolled

Overview

This is a research study where researchers are collecting blood to evaluate the genetic characteristics of individuals with chronic lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease, cystic fibrosis, and lung cancer.

The investigators hope to be able to identify an association between a genetic make-up in the blood samples and the risks of developing a particular lung disease, or severity of a lung disease. The findings of this study might be important to develop future preventative methods and potential treatments for the management of lung disease. The investigators aim to collect blood samples from 300 people with lung disease and 300 controls over 5 years.

Study Type

OBSERVATIONAL

Enrollment

3,087

Conditions

Asthma COPD Interstitial Lung Disease Cystic Fibrosis Lung Cancer

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Must provide informed consent * Males and females, age 18 years and older * Lung disease proven by at least one of the following: * symptoms consistent with pulmonary disease * chest X-rays consistent with lung disease * pulmonary function tests consistent with lung disease * lung biopsy consistent with lung disease * family history of lung disease * disease of organs with know associated with lung disease * individuals suspected of history of lung disease based on history and/or physical examination * normal controls (individuals without history of lung disease) to be sampled to provide a comparison to the lung disease cohort. Exclusion Criteria: * Drug and/or alcohol abuse within the past six months * Females who are pregnant or nursing

Locations (1)

New York Presbyterian Hospital -- Weill Cornell Medical College of Cornell University

New York, New York, United States

Outcomes

Primary Outcomes

Establish a set of normal ranges for various parameters in healthy individual specimens and compare to specimens from individuals with lung disease to determine parameters resulting in disease susceptibility and severity.

Time frame: 5 years

Data from ClinicalTrials.gov

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