Simvastatin Therapy in Women With Polycystic Ovary Syndrome.

Inclusion Criteria: * PCO - ESHRE/ASRM criteria: oligomenorrhea (\<8 spontaneous menses per year) and hyperandrogenism (hirsutism or acne) or hyperandrogenemia (testosterone \>70ng/dl) * Normal prolactin, TSH, 17-OH progesterone * No evidence of androgen producing malignancy, Cushing's syndrome or acromegaly * Age 18-40 * Reliable use of birth control pill for at least 3 months and no plans of pregnancy Exclusion Criteria: * Elevated creatinine kinase above 2 times upper limit of normal or liver enzymes (transaminases) above 2 times of upper limit of normal * Use of any of the following medications: cyclosporine, fibrates, niacin, antifungal agents, macrolide antibiotics. * Use of oral contraceptives and other steroid hormones 3 months prior to the study * Contraindications to oral contraceptives