Efficacy of Oral Colchicine in Prevention of Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment

Shahid Beheshti University of Medical Sciences

Overview

This clinical trial will test the efficacy and safety of oral colchicine in prevention of proliferative vitreoretinopathy (PVR) in cases of rhegmatogenous retinal detachment

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Conditions

Rhegmatogenous Retinal Detachment

Interventions

colchicineDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Rhegmatogenous retinal detachment Exclusion Criteria: * PVR grade C * Duration of retinal detachment ≥ one month * History of cataract surgery * History of RD surgery

Locations (1)

Hamid Ahmadieh,MD

Tehran, Tehran Province, Iran

Outcomes

Primary Outcomes

proliferative vitreoretinopathy

retinal reattachment rate

Secondary Outcomes

visual acuity

reoperation

macular pucker

Data from ClinicalTrials.gov

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