Intravitreal Triamcinolone for Acute Branch Retinal Vein Occlusion

Shahid Beheshti University of Medical Sciences30 enrolled

Overview

The purpose of this study is to determine whether intraocular injection of triamcinolone is effective in the treatment of macular edema in acute branch retinal vein occlusion.

Intravitreal triamcinolone has recently been shown to have beneficial effect on chronic macular edema due to vein occlusion and preventive effect on neovascularization. Hypothetically, prevention of macular derangement by reducing the amount of edema from early phase after occlusion until restoration of collaterals seems to be helpful in these eyes. To our knowledge, no prospective randomized clinical trial, considering both macular changes and preventive effect on neovascularization has been published for intravitreal triamcinolone in acute branch retinal vein occlusion.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Branch Retinal Vein Occlusion

Interventions

TriamcinoloneDRUG

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Eyes suffering from branch retinal vein occlusion with less than 2 months duration. Exclusion Criteria: * Monocularity, * Previous intraocular surgery or laser therapy * Glaucoma or ocular hypertension * Significant media opacity * Existence of traction on the macula * Visual acuity ≥20/40 * Signs of chronicity (such as cilioretinal and/or retinal shunt vessels)

Locations (1)

Alireza Ramezani, MD

Tehran, Tehran Province, Iran

Outcomes

Primary Outcomes

Central macular thickness

Secondary Outcomes

Visual acuity

Retinal neovascularization

Intraocular pressure

Cataract progression

Data from ClinicalTrials.gov

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