A Phase I Study of Pazopanib in Adult Patients With Liver Cancer

Inclusion criteria: * Diagnosis of advanced liver cancer adequate bone marrow, liver and kidney function * Any local therapy for tumor must have been completed at least 4 weeks prior to enrolling in study Exclusion criteria: * Pregnant or breastfeeding * Any serious or unstable medical or psychiatric conditions * History of metastases to central nervous system * History of ulcer, inflammatory bowel disease or disease of the gut * History of HIV, or uncontrolled infection * Have had a cardiac condition or stoke during the past 6 months * High blood pressure * Have had a blood clot during the past 6 months * History of bleeding blood vessels