Effect of Intravitreal Bevacizumab on Clinically Significant Macular Edema

Shahid Beheshti University of Medical Sciences150 enrolled

Overview

to compare the effect of intravitreal bevacizumab alone or in combination with triamcinolone acetonide with laser photocoagulation on clinically significant macular edema (CSME)

we entered 150 eyes into the study that recruitment of cases finished recently.Eligible eyes randomly assign to one of the study arms including intravitreal bevacizumzb, intravitreal bevacizumzb/triamcinolone and macular photocoagulation groups. Every patient needs at least 1 year followup. During this time BCVA, OCT, FA will be done for each patient and inaccording to interpretation of datas and fundus exam repeatation of injection will be done.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

150

Conditions

Diabetic Macular Edema

Interventions

bevacizumabDRUG

triamcinolone acetonideDRUG

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * case with clear media IOP below 23 mm/Hg female after menopause at least for 12 months or had 2 contraceptive roots visual acuity between 20/50 to 20/320 Exclusion Criteria: * no PRP or N.d YAG laser in past 6 months no intraocular surgery in past 12 months * CVA in past 12 months blood sugar above 250 * active infection in extraocular adnexa

Locations (1)

Masoud Soheilian

Tehran, Tehran Province, Iran

RECRUITING

Outcomes

Primary Outcomes

visual acuity

central macular thickness

Secondary Outcomes

Leakage in fluorescein angiography

intraocular pressure

cataract progression

anterior chamber reaction

Central Contacts

Masoud Soheilian, MD

CONTACT

+98 21 22585952 labbafi@hotmail.com

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.