The Effect of 5-FU and LMW Heparin on the Rate of Retinal Redetachment After Silicone Oil Removal in Cases of PVR

Shahid Beheshti University of Medical Sciences

Overview

To evaluate the effect of combined 5-FU and low molecular weight heparin in infusion on the rate of retinal redetachment after silicone oil removal in cases of proliferative vitreoretinopathy (PVR).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Conditions

Proliferative Vitreoretinopathy

Interventions

low molecular weight heparin, 5-FUDRUG

Eligibility

Sex: MALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Cases with history of vitrectomy and silicone oil injection for management of PVR who undergo silicone oil removal Exclusion Criteria: * any sign of retinal redetachment before silicone oil removal * any sign of diabetic retinopathy

Locations (1)

Hamid Ahmadieh, MD

Tehran, Tehran Province, Iran

Outcomes

Primary Outcomes

Retinal redetachment rate

Secondary Outcomes

visual acuity

intraocular pressure

reoperation

relative afferent pupillary defect

Data from ClinicalTrials.gov

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