IDEA-033 Open Label Study

Inclusion Criteria: * at least 18 years or older * agree to refrain from chronic usage of NSAIDs or any other analgesics or anti-inflammatory drugs other than those provided during the course of the study or documented sporadic concomitant analgesics * joint pain, musculoskeletal pain, stiffness, or soft tissue inflammation in designated target area(s) that are appropriate for self-treatment with a topical analgesic or where availability of a second person can be guaranteed in case self-treatment is not possible * healthy skin in the target area(s) Exclusion Criteria: * known hypersensitivity to IDEA-033 or other NSAIDs * history of coagulation disorders * history of peptic ulcers or gastric intolerance with NSAIDs * urinary tract infection * clinically significant renal, hepatic, or gastric disease * acute or chronic coexisting illness qualifying for exclusion according to clinical judgement of the investigator * clinical laboratory values outside normal range deemed clinically significant by the investigator * Narcotics-containing products within 7 days of administering IMP * Malignancy within the past 2 years