Safety and Efficacy Study of Transplantation of EPCs to Treat Idiopathic Pulmonary Arterial Hypertension

Inclusion Criteria: * Clinical diagnosis of idiopathic pulmonary arterial hypertension 1. in New York Heart Association (NYHA) functional class II to III 2. a mean pulmonary artery pressure more than 30 mmHg on right heart catheterization 3. the ability to walk ≥50 m during a standardized 6-minute walk test Exclusion Criteria: * Pulmonary hypertension as a result of heart disease, pulmonary disease, sleep-associated disorders, chronic thromboembolic disease, autoimmune or collagen vascular disease, HIV infection, liver disease, NYHA functional class IV, major bleeding requiring blood transfusion, diabetes, renal dysfunction, and evidence for malignant diseases were excluded