The purpose of this study is to determine if there is equivalence between two different methods of treating patients with severe bloodstream infection called sepsis. We will randomly assign patients to one of two treatment methods. One of the treatment methods is the current standard of care and uses an infrared sensor on the end of a catheter to determine the adequacy of treatment. The second treatment method is identical to the first but instead of the infrared sensor a blood test that is performed as a part of standard care (with blood drawn from the catheter) will be used to determine the adequacy of treatment. This study will attempt to determine an easier method of guiding treatment.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
300
Early goal directed therapy with lactate clearance
Early goal directed therapy
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
Cooper Hospital
Camden, New Jersey, United States
Carolinas Medical Center
Charlotte, North Carolina, United States
Mortality
Time frame: In-hospital
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