The Combined Effect of 2,3-Dimercaptosuccinic Acid and Multi-Nutrients on Children in Lead Poisoning

China Medical University, China500 enrolled

Overview

Lead poisoning remains a common disease among children despite successful public health efforts that reduced its prevalence.Our study was designed to test the hypothesis that lead-poisoning children (BLLs:100-440µg/L) who were given DMSA and multi-nutrients would have a greater fall than children of other groups at 12 weeks of follow-up.

Study Type

OBSERVATIONAL

Enrollment

500

Conditions

Lead Poisoning

Interventions

2,3-dimercaptosuccinic acidDRUG

Eligibility

Sex: ALLMin age: 3 YearsMax age: 6 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Initial BLLs 100-440µg/L * Age 3-6y * No more than two main residences * House cleaned (no lead contaminated) * Normal intake history and physical Exclusion Criteria: * Chelation in the past 12 weeks * Concomitant Fe deficiency(ferritin\<16ng/ml) * Hemoglobin\<10.5g/dL * Medications affecting mineral metabolism

Locations (1)

China Medical University

Shenyang, Liaoning, China

Data from ClinicalTrials.gov

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