Use of Clarithromycin in Mustard-Induced Bronchiolitis

Inclusion Criteria: * His/her own will to participate * Documented chemical exposure * Clinical, spirometric and radiological findings were compatible with BO on High Resolution Computed Tomography (HRCT) Exclusion Criteria: * any drug reactions during the trial * history of sensitivity to macrolides * diarrhea, gray stool, jaundice, eosinophilia, acute cholestatic hepatitis, pruritis, dark urine, abdominal pain, osteomatosis, depression, taste change, behavioural changes, early fatigue, odynophagia, glossitis , dizziness * co-adminstration of: terfenadine, theophylline, carbamazepine, ergotamine, dihydroergotamine, warfarin, cisapride, digoxin, triazolam, phenytoin, steroids, any immunosuppressive, any systemic antibiotics * using drugs that he/she cannot discontinue * using drugs with potential interaction * subject will to exit from the trial * history of lobe resection of lung * history of exacerbation in the last month prior to the beginning of trial * continuous need to oxygen * use of corticosteroids in last week prior to the trial beginning * Radiographic evidence of pneumonia, active tuberculosis, lung carcinoma, or an infection that necessitated the use of an antibiotic * exacerbating of subjects * creatinine srum level more than normal * increasing ALT, AST levels * total bilirubin more twice than normal * subjects who did not use their drugs properly