Chemoprevention of Cancer in the Lower Female Genital Tract: The Antineoplastic Activity of the Fungicide Ciclopirox.

Inclusion Criteria: * Patients between the ages 18 and 75 years. * Patients may be carriers of the Human Immunodeficiency Virus (HIV). * Patients must have been diagnosed with precancerous lesion(s) of the vulva by tissue sampling (biopsy-proven vulvar intraepithelial neoplasia grade II or III) * Patients must be able to come to University Hospital for their initial appointment in Gynecologic Oncology Clinic, and for the eight follow-up visits in that Clinic required by the protocol. Exclusion Criteria: * Pregnant or patients who are breast feeding a baby. * Patients who have been diagnosed with a vaginal yeast infection. * Patients who have undergone prior surgery for precancerous lesion(s) of the vulva.