The Effect of Beer, Red Wine and Fruit Juice on Blood Vessel Function in Persons With Cardiovascular Disease

Early Phase 1CompletedNCT00382551

Aalborg University Hospital49 enrolled

Overview

To study the effect of red wine, beer and fruit juice on endothelial function in patients with coronary Heart disease.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Coronary Heart Disease

Interventions

Moderate daily consumption of Red wineBEHAVIORAL

Moderate daily consumption of beerBEHAVIORAL

Moderate consumption of fruit juice rich in polyphenolicsBEHAVIORAL

Eligibility

Sex: ALLMin age: 30 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Men or postmenopausal women with stable coronary heart disease * Coronary heart disease should be verified by coronary angiography with at least 50% stenosis in at least one coronary vessel. Exclusion Criteria: * Patients with myocardial infarction within the last tree months * Persons with a present or earlier alcohol abuse * Persons with a present or earlier drug abuse * Person with malign disease * Persons, that we consider unsuitable to carry through the examines.

Locations (1)

Department of Cardiology, Aalborg Hospital, Science and Innovation Center

Aalborg, Aalborg, Denmark

Outcomes

Primary Outcomes

Changes in flow-mediated vasodilation after 2 weeks intervention compared with baseline

Secondary Outcomes

Lipid status after 2 weeks intervention compared with baseline

Effects in Coagulation factors after 2 weeks intervention

Effects on markers of inflammation after 2 weeks intervention

Effects on markers of endothelial function after 2 weeks intervention

Changes in the overall antioxidant activity in plasma after 2 weeks intervention

Data from ClinicalTrials.gov

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