To assess the safety and tolerability of repeated intravitreal (ITV) administration of VEGF Trap.
A double-masked study in which approximately 12 subjects will receive ITV injections of VEGF Trap every 4 weeks for a total of 3 doses. Once the subjects have received the 3 doses allowed in this study, they will be evaluated every 4 weeks for continued dosing of VEGF Trap for an additional 9 months.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
20
Unnamed facility
Fort Myers, Florida, United States
Unnamed facility
Wichita, Kansas, United States
Unnamed facility
Hagerstown, Maryland, United States
Unnamed facility
Columbia, South Carolina, United States
The primary endpoint of the study will be safety and tolerability of the study treatment at Week 12 as assessed by ophthalmic examination and reporting of AEs.
Time frame: 12 weeks
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Unnamed facility
Austin, Texas, United States
Unnamed facility
McAllen, Texas, United States