The purpose of this study is to compare the effect of arzoxifene to raloxifene on the bone mineral density (bone strength).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
320
20 mg, oral, tablet, once a day for 52 weeks
60 mg, oral, tablet, once a day for 52 weeks
Percent change in Lumbar Spine BMD
Time frame: baseline to 12 months
Secondary BMD measures of total hip and femoral neck
Time frame: at 6 and 12 months
Biochemical markers of bone metabolism assessed
Time frame: baseline, 3, 6, and 12 months
Assessment of coagulation parameters
Time frame: baseline, 3, 6, and 12 months
Breast Density by mammogram
Time frame: screening and 12 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Gainesville, Georgia, United States
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Urbandale, Iowa, United States
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Billings, Montana, United States
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Cincinnati, Ohio, United States
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Houston, Texas, United States
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Buenos Aires, Argentina
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Randwick, New South Wales, Australia
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Vancouver, British Columbia, Canada
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Halifax, Nova Scotia, Canada
For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
Toronto, Ontario, Canada
...and 11 more locations