A Phase III Trial Comparing UFT+PSK to UFT+LV in Stage IIB, III Colorectal Cancer

Inclusion Criteria: * Patients with pTNM stage IIB or III (UICC Sixth version) primary colon cancer/rectal cancer who have undergone surgery of histological curability A (including laparoscopic surgery) (the curability is judged after surgery) * Patients with primary tumor that directly invades other organs or structures and/or perforates into the visceral peritoneum (T4) or with histologically positive lymph node metastasis (N+) (to be judged after surgery) * Patients who is between 20 and 80 years old at the time of obtaining informed consent * Patients with performance status of 0 - 2 * Patients without receiving any cancer treatment such as radiation, chemotherapy, and immunotherapy before surgical operation * Patients without severe dysfunction of renal, hepatic, or bone marrow function * Patients without serious complications such as bone marrow suppression, diarrhea, and infections diseases * Patients who have given consent to participate in this clinical study by himself/herself or his/her family Exclusion Criteria: * Patients in whom the bottom of tumor reaches the peritoneal reflection * Patients with lower rectal cancer (Rb), anal canal (P), or circumanal skin (E) * Patients who has active multiple cancers or whose disease-free survival is less than 5 years even though the cancers are metachronous (except carcinoma in situ and skin cancers) * Women who are currently pregnant or wish to be pregnant during this clinical study * Patients who are judged to be inappropriate to participate in this clinical study by the investigator or subinvestigator