Rimonabant in Obesity Over a 2-Year Duration (RIO-Europe)

Inclusion Criteria: * body mass index (BMI) e30 kg/m2 in patients with or without comorbidities, or BMI \>27 kg/m2 in patients with treated or untreated hypertension and/or treated or untreated dyslipidemia. * stable body weight (variation \<5 kg within 3 months prior to screening visit); Exclusion Criteria: * History of very low-calorie diet within 6 months prior to screening visit; or history of surgical procedures for body weight loss (eg, stomach stapling, bypass); * Presence of any clinically significant psychiatric , neurological or endocrine disease * Presence of treated or untreated type 1 or type 2 diabetes); * SBP \>165 mmHg and/or DBP \>105 mmHg on 2 consecutive visits from the screening to the inclusion visit; * History of myocardial infarction or unstable angina pectoris within 6 months prior to screening visit; and history of stroke within 6 months prior to screening visit; * Administration of anti-obesity drugs or other drugs for body weight reduction within 3 months prior to screening visit; The investigator will evaluate whether there are other reasons why a patient may not participate.