Somatosensory Processing in Depression

Ludwig-Maximilians - University of Munich

Overview

Aim of this study is to investigate neuronal differences (EEG/evoked potentials; functional MRI) between patients with major depression and healthy controls concerning brain activity after acute pain as well as changes of pain related brain activity during treatment with escitalopram.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Conditions

Depression

Interventions

simultaneous EEG/fMRIPROCEDURE

fMRI/EEG recordings

fMRIDEVICE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Psychiatric in or outpatients with acute depressive episode * Indication for pharmacological treatment Exclusion Criteria: * Acute suicidal tendency * Neurological or severe somatic disorders * Women during pregnancy or lactation

Locations (1)

Department of Psychiatry and Clin. Radiology, Ludwig-Maximilian-University

Munich, Bavaria, Germany

Outcomes

Primary Outcomes

changes in evoked potentials/functional MRI from baseline to week 4

Time frame: two assessments, at baseline and week 4

Data from ClinicalTrials.gov

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