Efficacy and Safety of Intranasal Morphine for Pain After Third Molar Extraction

Inclusion Criteria: * Male or female 18-40 years of age * Surgical extraction of at least three or more third molars (two must be mandibular and both must be bony impacted third molars) * Moderate or severe pain within 6 hours of completion of surgery Exclusion Criteria: * Other oral surgical procedures during the same session except the removal of supernumerary third molars * Evidence of nasal congestion, nasal polyps, mucosal lesions of the nostrils, postnasal drip of any etiology or any clinically significant nasal pathology that may affect the absorption of study medication or the assessment of safety * Chronic respiratory insufficiency such that treatment with an opioid analgesic is contraindicated * Allergy to shellfish Additional Inclusion/Exclusion Criteria May Apply