Changes in Cerebrovascular Reactivity During Cognitive Activation After Cardiopulmonary Bypass: Relation With Intraoperative Embolic Load and Postoperative Neuropsychological Dysfunctions

University Ghent66 enrolled

Overview

The study aims to evaluate neuropsychological disorders in CABG patients. Measurements are performed 1 day before, 6 days, 6 months and 3-5 years after the surgery. The relation with cerebrovascular reactivity and embolic load (measured by transcranial Doppler Ultrasonography) is evaluated. Two surgery techniques (on- and off-pump CABG) are compared.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

CABG-Patients

Interventions

Determination of neuropsychological statusPROCEDURE

Eligibility

Sex: ALLMin age: 18 YearsMax age: 69 Years

Medical Language ↔ Plain English

Inclusion Criteria: * CABG-patients (not urgent) * \< 70 years old * Righthanded Exclusion Criteria: * Neurological or psychiatric disease * Psychoactive medication * Valve operation

Locations (1)

University Hospital Ghent

Ghent, Belgium

Outcomes

Primary Outcomes

Neuropsychological status

Time frame: after 6 days, 6 months and 3-5 years

Secondary Outcomes

Relation with intra-operative embolic load

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.