Individualized, Target-Driven Treatment Of Children With Idiopathic Short Stature

Variability of Height SDS at 24 Months

The continuous endpoint of variability of height SDS at 24 months was defined as the SD of the 24 month height SDS.

Time frame: 2 years

Time Cost (Months Until >= -2 SDS)

Time cost was defined as the number of months needed until height SDS was within the normal limit (ie, \>= -2SDS).

Time frame: 2 years

Computed Cost of Height Gain at 48 Months

The computed cost of height gain was defined as the amount of drug used relative to the observed height-gain, in terms of mg/cm, this was calculated at Month 48.

Time frame: 4 years

Estimated Cost of Height Gain Estimated Until Full Adult Height (FAH) at 48 Months

The estimated cost of long-term height gain until FAH was calculated.

Time frame: 4 years

Change From Baseline in Height SDS at 48 Months.

Change in height SDS was measured at 48 months.

Time frame: 4 years