The purpose of this study is to determine the ability of a proprietary software screening tool to discriminate normal corneas (front surface of the eye) from previously diagnosed corneal conditions (diseases/surgeries/pathologies) and to determine the repeatabiltity and reproducibility of the Atlas II corneal topographer in normal human corneas.
1. To establish reference values for SF, CIM, and TKM in subjects with normal corneas. 2. To establish reference values for SF, CIM, and TKM in subjects who underwent myopic laser vision correction. 3. To establish reference values for SF, CIM, and TKM in subjects who underwent hyperopic laser vision correction. 4. To establish reference values for SF, CIM, and TKM in subjects who were diagnosed to have keratoconus. 5. To establish reference values for SF, CIM, and TKM in subjects with history of orthokeratology. 6. To establish reference values for SF, CIM, and TKM in subjects with previously diagnosed corneal conditions (diseases/pathologies/surgeries) affecting the corneal surface that are not listed above. 7. To determine the repeatabiltity and reproducibility of the Atlas II corneal topographer in normal human corneas using true elevation data and axial curvature. 8. To determine the sensitivity, specificity, and accuracy of the Pathfinder II Corneal Analysis software in discriminating normal corneas from previously diagnosed corneal conditions (diseases/pathologies/surgeries) affecting the corneal surface (Phase II).
Study Type
OBSERVATIONAL
Enrollment
769
Shiley Eye Center-University of California San Diego
La Jolla, California, United States
Carmel Mountain Vision Care Center
San Diego, California, United States
Dishler Laser Institute
Greenwood Village, Colorado, United States
Pacific University
Forest Grove, Oregon, United States
Reference values of normal and previously diagnosed corneal conditions by Atlas II corneal topographer
Time frame: 1-2 hours
Repeatabiltity and reproducibility of the Atlas II corneal topographer in human corneas
Time frame: 1-2 hours
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