The Role of the Vagus Nerve in Tumor-to-Brain Communication in Lung Cancer Patients

Rambam Health Care Campus40 enrolled

Overview

the aim of this study is to measure brain metabolism in patients with lung cancer.FDG uptake in the brain in patients with malignant tumors will be compared to the amount of tracer activity found in patients who have benign pulmonary process. if differences between the brain uptake of FDG in the two groups will be found, further assessment will be performed in order to evaluate if such differences could be attributed and specifically localized to the brain regions innervated by the vagus

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

NONE

Enrollment

Conditions

Lung Cancer

Interventions

PET/CT imagingDEVICE

Eligibility

Sex: ALLMin age: 35 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients with SPN referred for routine whole body FDG-PET imaging * patients with NSCLC and patients with no evidence of lung cancer on further follow up Exclusion Criteria: * patients with a clinical history of vagotomy, abdominal surgery. brain tumor, brain trauma or CVA. or those with a systemic inflammatory disease

Locations (1)

Rambam Medical Center

Haifa, Israel

RECRUITING

Outcomes

Primary Outcomes

the impact of the imaging modality on patients management

Secondary Outcomes

the impact of the imaging modality on patients management

Central Contacts

Alex Frenkel, Ph.D

CONTACT

972-4-8543009 a_frenkel@rambam.health.gov.il

Data from ClinicalTrials.gov

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