Evaluation of the Antihypertensive Effect of Hyzaar(R) and Cognitive Function of Hypertensive Patients (0954A-322)

Inclusion Criteria: * ACEi or ARB naive or not taking ACEi or ARB concurrently for at least one month before the run-in period * Be able to carry out his or her own daily activity * \- Be at least 50 years old at inclusion in the study Be diagnosed with mild to moderate hypertension, treated or untreated * Literate * Not taking any cognitive-enhanced agent at baseline * Present with a memory complain ( spontaneous or informed by caregiver) Exclusion Criteria: * Congestive heart failure with NYHA class \>2 * Renal failure or renal insufficiency with serum creatinine \>1.4mg/dl * chronic severe liver disease with abnormal GPT and GOT \>2 times of upper normal limits * Diagnosed with major depression when entering the study * Foreign language as his or her mother tongue so that the test results will not be reliable * History of stroke or transient ischemic attack (stroke is defined as focal neurological sign progressing stepwise) * Hypersensitive to the active ingredient and any other component of losartan potassium and indapamide tablets * Major hearing loss/deafness and/or major visual impairment/blindness preventing from performing the tests * Myocardial infarction within the past 6 months * Single functioning kidney * Anuria