The purpose of this study is to determine whether the investigational drug INCB013739 has an effect on systemic and adipose tissue 11-HSD1 activity in obese, insulin resistant subjects.
"Proprietary Information: Exploratory (Non-Confirmatory) Trial".
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Unnamed facility
Beverly Hills, California, United States
Unnamed facility
Chula Vista, California, United States
Assessment of pharmacokinetics of INCB013739 through analysis of blood samples.
Time frame: Serial collections at each visit
Evaluation of change in cortisol laboratory values
Time frame: Serial collections at each visit
Assessment of ECGs, laboratory results and physical exams for adverse events
Time frame: Measured from baseline through study completion
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