A Test of Iron Malabsorption in Patients With Iron Deficiency Anemia

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)15 enrolled

Overview

The objective of the study is to develop a simple, noninvasive test for evaluation of iron absorption as a tool to determine the cause of iron deficiency anemia. Healthy, premenopausal women with iron deficiency with or without anemia will be recruited for the study. Participants will, over the course of two months, ingest an iron solution three times; after each iron ingestion, participants will collect their stool and bring it to the study investigators for assessment of iron content.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Iron Deficiency Anemia

Interventions

stable isotope of iron, dysprosiumDRUG

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * ferritin \<40 Exclusion Criteria: * pregnant, * post-partum, * s/p GIT surgery, * known malabsorption, * coeliac disease, * Helicobacter pylori

Locations (1)

UT Southwestern

Dallas, Texas, United States

Outcomes

Primary Outcomes

initial mucosal uptake of iron

intra- and inter-individual variability

red cell incorporation of iron

Data from ClinicalTrials.gov

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