Efficacy & Safety Study of Recombinant Human Erythropoietin -Alpha, in Patients With Anemia of Chronic Renal Failure

Inclusion Criteria: * Patients between 18 to 70 yrs of age of either sex. * CRF patients who are EPO naïve or have been off EPO or similar Erythropoietic drugs for more than 4 weeks, falling with-in CKD stage III to V. * Patients who are willing to give the consent * Patient with Anemia of Chronic Renal Failure with Hb \< 10. Exclusion Criteria: * Patients who are known hypersensitive to rHu-EPO. * Patient's with history of anemia due to causes other than anemia of CRF. * Patient's with history of Active infections, Hemoglobinopathies, Neoplastic diseases, and HIV infection. * Patient's with history of G.I. bleeding (Overt or Occult). * Patient's with history of serious or unstable medical or psychological conditions that could compromise the patient's safety or successful trial participation. * Patients with abnormal liver function test. However, patients with HBsAg and HCV positive shall be included provided their Transaminases are normal. * Female patient's of child bearing potential and not having undergone permanent sterilization procedures. Pregnant and lactating female patients. * Patients unwilling or unable to comply with the study procedures. Chronic alcoholic or drug abuse patients