A Study of LX211 in Active Sight Threatening, Non-infectious Intermediate-, Anterior and Intermediate-, Posterior-, or Pan-Uveitis

Inclusion Criteria: * Documented history of non-infectious intermediate-, anterior and intermediate-, posterior- or panuveitis uveitis * Current uveitis therapy must conform to one of the following: 1. Prednisone monotherapy at a dose of ≥ 10 mg/day (or equivalent) for ≥ 2 weeks prior to randomization 2. Have received ≥ 2 injections of corticosteroid (intravitreal or periocular) for control of disease within the past 8 months, but not within 2 weeks of randomization; subjects may also be receiving systemic corticosteroid therapy 3. Receiving monotherapy with azathioprine, mycophenolate mofetil, mycophenolic acid or methotrexate for at least 2 weeks prior to randomization 4. Receiving prednisone in addition to one immunomodulatory agent from among cyclosporine, tacrolimus, azathioprine, mycophenolate mofetil, mycophenolic acid and methotrexate for at least 2 weeks prior to randomization 5. Subjects for whom corticosteroid therapy (systemic or local) is medically inappropriate or who refuse corticosteroid therapy * Grade of 2+ or higher for vitreous haze at time of enrollment * Considered by the investigator to require immunomodulatory therapy. * Not planning to undergo elective ocular surgery during the study Exclusion Criteria: * Uveitis of infectious etiology * Clinically suspected or confirmed central nervous system or ocular lymphoma * Primary diagnosis of anterior uveitis