Corneal Barrier Function With Multi-Purpose Solutions

Southern California College of Optometry at Marshall B. Ketchum University25 enrolled

Overview

The purpose of this study is to evaluate the effect on epithelial barrier function of three emarketed multi-purpose solution applied to the human eye with hydrogel lenses as during normal regimen use.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Contact Lens Care

Interventions

Multi-purpose solutions (polyquaternium-1 and PHMB)DEVICE

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Adapted daily soft contact lens wearers, at least 18 years of age, vision correctable to 20/40 Exclusion Criteria: * Ocular or systemic allergies, abnormalities of the cornea, active ocular infection, prior keratorefractive surgery, use of ocular medications

Locations (1)

Southern California College of Optometry

Fullerton, California, United States

Outcomes

Primary Outcomes

Ratio of fluorescein dye penetration rate of test eye vs. control

Secondary Outcomes

Corneal fluorescein staining

Data from ClinicalTrials.gov

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