The primary purpose of this study is to determine the maximum tolerated dose and dose-limiting toxicities (DLTs) of weekly and every 3-weeks ABI-007 in combination with carboplatin (area under the curve \[AUC\]=6) in patients with ovarian cancer, primary peritoneal cancer, or fallopian tube cancer.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
6
80mg/m\^2 to 150mg/m\^2 IV every 3 weeks
6 AUC IV every 3 weeks on the same day as ABI-007
University of Texas, MD Anderson Cancer Center
Houston, Texas, United States
Primary: Safety/tolerability endpoints are the maximum tolerated dose and dose-limiting toxicities
Time frame: 18 months
Safety-AEs, SAEs, Lab abnormalities, incidence of patients experiencing dose modification of those interruptions &/or premature of d/c pf study drug
Time frame: Patient progression or until discontinuation
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