PROTECT : Pacing to Protect Heart for Damage From Blocked Heart Vessel and From Re-opening Blocked Vessel(s)

Inclusion Criteria: * Clinical diagnosis of acute myocardial infarction, requiring PCI within 2 to 6 hours following symptoms * Total occlusion of a coronary artery with reference vessel diameter \>or= 3mm Exclusion Criteria: * Thrombolitics * Severe bradycardia requiring cardiac pacing * Previous PCI or CABG * Recent stroke or CV surgery * Recent major surgery or trauma * Clinical and hemodynamic unstability * Implanted CRM device * Evidence of previous MI * Diabetes using rosiglitazone or other fibrates * Permanent AF * Mechanical tricuspid valve * Pregnancy * Exclusion for MRI * Incapability of participating in exercise test